NVL rabbit pAb

SKU: ES3777

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Mouse;Rat

Dilution:Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Immunogen:Synthesized peptide derived from NVL . at AA range: 320-400

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):95kD

Human_gene_id:4931

Human_swiss_prot_no:O15381

Subcellular_location:[Isoform 2]: Nucleus, nucleoplasm .; [Isoform 1]: Nucleus, nucleolus . Nucleus, nucleoplasm . Expressed predominantly in the nucleolus. Associates with pre-ribosomal particles in the nucleus. .

Other_name:NVL; Nuclear valosin-containing protein-like; NVLp; Nuclear VCP-like protein

Background:This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin. [provided by RefSeq, Aug 2011],