NRG1 Antibody - Cat. #: CSB-PA211518

SKU: CSB-PA211518

Size :100ul

Clone Number:

Aliases:Pro-neuregulin-1; membrane-bound isoform; Pro-NRG1; NRG1; GGF

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15491

Immunogen:Synthesized peptide derived from Human NRG1 isoform-10.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:The protein encoded by this gene is a membrane glycoprotein that that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

Xiao-Feng Le, Cancer Res., Jul 2000; 60: 3522 - 3531.
Samuel D. H. Chan, J. Biol. Chem., Sep 1995; 270: 22608.
Daniel C. Gamett, J. Biol. Chem., Aug 1995; 270: 19022.
Mohammed Rahmatullah, Mol. Cell. Biol., Nov 1998; 18: 6245 - 6252.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NRG1

Research Areas:Neuroscience;Signal transduction