NR1I2 Antibody - Cat. #: CSB-PA016048ESR1HU

SKU: CSB-PA016048ESR1HU

Size :50ul

Clone Number:

Aliases:BXR antibody; Nr1i2 antibody; NR1I2_HUMAN antibody; Nuclear receptor subfamily 1 group I member 2 antibody; ONR 1 antibody; ONR1 antibody; Orphan nuclear receptor PAR 1 antibody; Orphan nuclear receptor PAR1 antibody; Orphan nuclear receptor PXR antibody; OTTHUMP00000215173 antibody; OTTHUMP00000215174 antibody; OTTHUMP00000215175 antibody; PAR 1 antibody; PAR 2 antibody; PAR antibody; PAR q antibody; PAR1 antibody; PAR2 antibody; PARq antibody; pregnane X nuclear receptor variant 2 antibody; Pregnane X receptor antibody; PRR antibody; PXR antibody; SAR antibody; Steroid and xenobiotic receptor antibody; SXR antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O75469

Immunogen:Recombinant Human Nuclear receptor subfamily 1 group I member 2 protein (175-434AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NR1I2

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Metabolism; Signal transduction