NPHP3 Rabbit Polyclonal Antibody

SKU: BT-AP03852

Size:100μL

Background:This gene encodes a protein containing a coiled-coil (CC) domain| a tubulin-tyrosine ligase (TTL) domain| and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin| it is required for normal ciliary development| and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3| and also with renal-hepatic-pancreatic dysplasia| and Meckel syndrome type 7. Naturally occurring read-through transcripts exist between this gene and the downstream ACAD11 (acyl-CoA dehydrogenase family| member 11) gene.

Research_area:Signal transduction

Target_protein:NPHP3

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:NPHP3

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):146300

UniProt accession:Human: Q7Z494; Mouse: Q7TNH6

Synonyms:NPHP3

GeneID:Human: 27031; Mouse: 74025