NOS1 Polyclonal Antibody

SKU: E-AB-70065

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:NOS1

Target Synonym:2310005C01Rik;BNOS;Constitutive NOS;EC 1.14.13.39;IHPS 1;IHPS1;N-NOS;NC-NOS;neuronal Nitric Oxide Synthase;Neuronal NOS;Nitric oxide synthase;neuronal;included;Nitric oxide synthase 1 (neuronal);Nitric oxide synthase 1;Nitric oxide synthase;brain;Nitric oxide synthase;penile neuronal;included;NNOS;NO;NOS 1;NOS;NOS type I;NOS-I;NOS1;NOS1;Peptidyl-cysteine S-nitrosylase NOS1

Research Areas:Cancer;Metabolism;Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P29475,P29476,Q9Z0J4

Accession:

Background:The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.

Concentration:350 μg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse nNOS

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IHC 1:300-1:800

Calculated MW:161kDa

ObservedMW:161kDa