NFIL3 antibody , Cat. # FNab05700

SKU: FNab05700

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor(ATF) sites. Represses promoter activity in osteoblasts(By similarity). Represses transcriptional activity of PER1(By similarity). Represses transcriptional activity of PER2 via the B-site on the promoter(By similarity). Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors(DBP, HLF and TEF)(By similarity). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock(By similarity). Protects pro-B cells from programmed cell death(By similarity).

Immunogen:nuclear factor, interleukin 3 regulated

Synonyms:E4BP4, IL3BP1

Observed MW:55-60 kDa

Uniprot ID:Q16649

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IP

Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:2000

Gene ID:4783

Research Area:Neuroscience, Metabolism