NFATc4(Phospho Ser676) Polyclonal Antibody

SKU: BT-AP02222

Size:100μL

Background:This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase| calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells| especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants.

Research_area:Epigenetics and nuclear signaling; Immunology; Signal transduction

Target_protein:NFATC4

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Nuclear factor of activated T-cells cytoplasmic 4

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):95473

UniProt accession:Human: Q14934; Mouse: Q8K120

Synonyms:Nuclear factor of activated T-cells cytoplasmic 4; NFATC4; NFAT3; Nuclear factor of activated T-cells; cytoplasmic 4; NF-ATc4; NFATc4; T-cell transcription factor NFAT3; NF-AT3

GeneID:Human: 4776; Mouse: 73181