NF-L antibody , Cat. # FNab05710

SKU: FNab05710

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)

Background:Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Immunogen:neurofilament, light polypeptide

Synonyms:68 kDa neurofilament protein, CMT1F, CMT2E, FLJ53642, NEFL, NF L, NF68, NFL

Observed MW:72 kDa

Uniprot ID:P07196

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IF

Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:100 - 1:1000; IF: 1:50 - 1:200

Gene ID:4747

Research Area:Neuroscience, Stem Cells, Immunology