GeneBio Systems
NDUS2 Polyclonal Antibody
NDUS2 Polyclonal Antibody
SKU:BT-AP11781
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Size:100μL
Background:The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research_area:Cancer; Cell biology; Metabolism; Signal transduction; Tags & cell markers
Target_protein:NDUFS2
applications:WB, ELISA
Reactivity:Human, Rat, Mouse
Clonality:Polyclonal
Clone ID:
Host:Rabbit
Isotype:IgG
Gene Symbol/ Name:NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Storage:-20°C for 1 year
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Molecular weight(Da):
UniProt accession:Human: O75306; Mouse: Q91WD5; Rat: Q641Y2
Synonyms:NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial ;EC 1.6.5.3;EC 1.6.99.3;Complex I-49kD;CI-49kD;NADH-ubiquinone oxidoreductase 49 kDa subunit
GeneID:Human: 4720
