NCR2 Polyclonal Antibody

SKU: E-AB-13122

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:NCR2

Target Synonym:Activating NK receptor NKp44;CD336;CD336 antigen;dJ149M18.1;LY95;Lymphocyte antigen 95 (activating NK receptor;NK p44);Lymphocyte antigen 95 homolog (activating NK receptor;NK p44);Lymphocyte antigen 95 homolog;Lymphocyte antigen 95;mouse;homolog of;Natural cytotoxicity triggering receptor 2;Natural killer cell p44 related protein;Natural killer cell p44-related protein;NCR2;NCTR2;NK cell activating receptor (NKp44);NK cell activating receptor;NK cell-activating receptor;NK p44;NK-p44;NKp44

Research Areas:Cancer;Immunology;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:O95944

Accession:

Background:Natural cytotoxicity triggering receptor 2is aproteinthat in humans is encoded by theNCR2gene. NCR2 has also been designated asCD336(cluster of differentiation336). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.

Concentration:0.6 mg/mL

Immunogen:Synthetic peptide of human NCR2

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:IHC 1:50-1:200

Calculated MW:

ObservedMW: