NCOR1 Monoclonal Antibody

SKU: BT-MCA4264

Size:100μL

Background:NCOR1: Nuclear receptor co-repressor 1. This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:NCOR1

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:7A7A9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:NCOR1

Immunogen:Purified recombinant fragment of NCOR1 (aa1-192) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:O75376

Synonyms:N-CoR, TRAC1, hN-CoR

GeneID:9611