NCOA6 antibody , Cat. # FNab05591

SKU: FNab05591

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist-and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids(GR and ERs), retinoids(RARs and RXRs), thyroid hormone(TRs), vitamin D3(VDR) and prostanoids(PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.

Immunogen:nuclear receptor coactivator 6

Synonyms:AIB3, KIAA0181, RAP250, TRBP

Observed MW:68 kDa ; 219 kDa ; 110 kDa

Uniprot ID:Q14686

Reactivity:Human, Mouse

Tested Application:ELISA, IP

Recommended dilution:IP: 1:200-1:2000

Gene ID:23054

Research Area:Metabolism