NCOA3 antibody , Cat. # FNab05589

SKU: FNab05589

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids(GR and ER), retinoids(RARs and RXRs), thyroid hormone(TRs), vitamin D3(VDR) and prostanoids(PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.

Immunogen:nuclear receptor coactivator 3

Synonyms:AIB1, BHLHE42, RAC3, TRAM1

Observed MW:160kd

Uniprot ID:Q9Y6Q9

Reactivity:Human

Tested Application:ELISA, WB, IF, IHC, FC

Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID:8202

Research Area:Metabolism