NBN Polyclonal Antibody

SKU: E-AB-15798

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: NBN

Target Synonym: AT V1;AT V2;ATV;Cell cycle regulatory protein p95;FLJ10155;MGC87362;Nbn;NBN;NBS 1;NBS;NBS1;Nibrin;Nijmegen breakage syndrome 1 (nibrin);Nijmegen breakage syndrome;Nijmegen breakage syndrome protein 1;p95;p95 protein of the MRE11/RAD50 complex

Research Areas: Cancer;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O60934

Accession:

Background: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Concentration: 0.5 mg/mL

Immunogen: Synthetic peptide of human NBN

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:25-1:100

Calculated MW:

ObservedMW: