NAT8 Antibody, Biotin conjugated - Cat. #: CSB-PA887033LD01HU

SKU: CSB-PA887033LD01HU

Size :50ug

Clone Number:

Aliases:acetyltransferase 2 antibody; ATase2 antibody; Camello, Xenopus, homolog of, 1 antibody; Camello-like protein 1 antibody; CML1 antibody; cysteinyl-conjugate N-acetyltransferase antibody; GLA antibody; Hcml1 antibody; kidney- and liver-specific gene product antibody; N-acetyltransferase 8 (camello like) antibody; N-acetyltransferase 8 (GCN5-related, putative) antibody; N-acetyltransferase 8 antibody; NAT8 antibody; NAT8_HUMAN antibody; Probable N-acetyltransferase 8 antibody; TSC501 antibody; TSC510 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UHE5

Immunogen:Recombinant Human N-acetyltransferase 8 protein (64-227AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Acetylates the free alpha-amino group of cysteine S-conjugates to form mercapturic acids (PubMed:20392701). This is the final step in a major route for detoxification of a wide variety of reactive electrophiles which starts with their incorporation into glutathione S-conjugates. The glutathione S-conjugates are then further processed into cysteine S-conjugates and finally mercapturic acids which are water soluble and can be readily excreted in urine or bile. Alternatively, may have a lysine N-acetyltransferase activity catalyzing peptidyl-lysine N6-acetylation of various proteins. Thereby, may regulate apoptosis through the acetylation and the regulation of the expression of PROM1 (PubMed:24556617). May also regulate amyloid beta-peptide secretion through acetylation of BACE1 and the regulation of its expression in neurons (PubMed:19011241).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NAT8

Research Areas:Developmental biology; Metabolism; Signal transduction