NANOS3 Antibody - Cat. #: CSB-PA015438LA01HU

SKU: CSB-PA015438LA01HU

Size :50ug

Clone Number:

Aliases:NANO3_HUMAN antibody; Nanos homolog 3 antibody; NANOS3 antibody; NOS-3 antibody; Nos3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P60323

Immunogen:Recombinant Human Nanos homolog 3 protein (21-192AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background:Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NANOS3

Research Areas:Epigenetics and Nuclear Signaling; Cell biology; Developmental biology; Stem cells