MTSS1 Antibody - Cat. #: CSB-PA098234

SKU: CSB-PA098234

Size :50ul

Clone Number:

Aliases:2310003N14Rik antibody; BC024131 antibody; D130001D01Rik antibody; DKFZp781P2223 antibody; FLJ44694 antibody; KIAA0429 antibody; metastasis suppressor 1 antibody; Metastasis suppressor protein 1 antibody; Metastasis suppressor YGL 1 antibody; Metastasis suppressor YGL-1 antibody; MGC37896 antibody; MIM antibody; MIMA antibody; MIMB antibody; missing in metastasis antibody; Missing in metastasis protein antibody; mKIAA0429 antibody; MTSS 1 antibody; Mtss1 antibody; MTSS1_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O43312

Immunogen:Synthetic peptide of Human MTSS1

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100

Background:MTSS1 (metastasis suppressor 1), also known as MIM, MIMA or MIMB, is a 755 amino acid protein that contains one Actin-binding WH2 (Wiskott-Aldrich syndrome protein homology-2) domain and one IMD domain. Expressed in a variety of tissues including testis, thymus, prostate, spleen, colon, uterus and blood, MTSS1 is thought to bind to Actin and, via this binding, may affect the dynamics of the cytoskeleton. Through its association with the cytoskeleton, MTSS1 plays a role in controlling the progression and metastasis of carcinomas in various organ sites throughout the body and, when expressed at normal levels, functions as a tumor suppressor. Overexpression of MTSS1 results in the formation of abnormal actin structures, an event that may lead to tumorigenesis. Three isoforms of MTSS1 exist due to alternative splicing events.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MTSS1

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Signal transduction