MRPL40 Polyclonal Antibody

SKU: E-AB-53084

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:MRPL40

Target Synonym:39S ribosomal protein L40;39S ribosomal protein L40 mitochondrial;39S ribosomal protein L40;mitochondrial precursor;FLJ41774;L40mt;MGC9400;mitochondrial;Mitochondrial ribosomal protein L40;MRP 40;MRP L22;MRP-L40;MRP40;MRPL22;MRPL40;NLVCF;Nuclear localization signal containing protein deleted in velocardiofacial syndrome;Nuclear localization signal deleted in velocardiofacial syndrome;Nuclear localization signal-containing protein deleted in velocardiofacial syndrome;RM40;Up-regulated in metastasis;URIM

Research Areas:Epigenetics and Nuclear Signaling;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q9NQ50

Accession:

Background:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.MRPL40 (Mitochondrial Ribosomal Protein L40) is a Protein Coding gene. Diseases associated with MRPL40 include Mrpl40-Related Disorder and Velocardiofacial Syndrome. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. GO annotations related to this gene include poly(A) RNA binding.

Concentration:0.78 mg/mL

Immunogen:Fusion protein of human MRPL40

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:50-1:200

Calculated MW:

ObservedMW: