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GeneBio Systems

MRE11 Polyclonal Antibody

MRE11 Polyclonal Antibody

E-AB-11403

$493.92 CAD
$493.92 CAD
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Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:MRE11A

Target Synonym:AT like disease;Ataxia telangiectasia disorder like;ATLD;DNA recombination and repair protein;Double strand break repair protein MRE11A;Double-strand break repair protein MRE11A;endo/exonuclease Mre11;HNGS1;meiotic recombination (S. cerevisiae) 11 homolog A;Meiotic recombination 11 homolog 1;meiotic recombination 11 homolog A (S. cerevisiae);Meiotic recombination 11 homolog A;MmMRE11A;Mre 11;MRE 11a;MRE 11b;MRE11 homolog 1;MRE11 homolog A;MRE11 homolog double strand break repair nuclease;MRE11 meiotic recombination 11 homolog A (S. cerevisiae);MRE11 meiotic recombination 11 homolog A;MRE11;MRE11A;MRE11b;OTTHUMP00000236830;OTTHUMP00000236831;OTTHUMP00000236832;OTTHUMP00000236833

Research Areas:Cancer;Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P49959

Accession:

Background:This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Concentration:0.6 mg/mL

Immunogen:Recombinant protein of human MRE11A

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IHC 1:100-1:300

Calculated MW:81kDa

ObservedMW:

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