Mouse Zinc finger E-box-binding homeobox 1 ,ZEB1 ELISA KIT

SKU: E1148Mo

Size:96 Tests-1 Kit

Background:Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1 (By similarity). Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs. {ECO:0000250, ECO:0000269|PubMed:19935649, ECO:0000269|PubMed:20346398}.

Research_area:

Applications:ELISA

Target_protein:Zeb1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.21ng/ml

Detection range:0.38-24ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Zinc finger E-box-binding homeobox 1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q64318

MASS(Da):122465

GeneID:21417

Synonyms:Zeb1 Tcf8 Zfhx1a Zfx1a Zfx1ha

Gene names:Zeb1

Standard solution:48ng/ml