Mouse Tyrosine-protein Phosphatase Non-receptor Type 4, PTPN4 ELISA Kit

SKU: E2548Mo

Size:96 Tests-1 Kit

Background:Phosphatase that plays a role in immunity, learning, synaptic plasticity or cell homeostasis (PubMed: 17953619, PubMed: 25825441). Regulates neuronal cell homeostasis by protecting neurons against apoptosis (By similarity). Negatively regulates TLR4-induced interferon beta production by dephosphorylating adapter TICAM2 and inhibiting subsequent TRAM-TRIF interaction (PubMed: 25825441). Dephosphorylates also the immunoreceptor tyrosine-based activation motifs/ITAMs of the TCR zeta subunit and thereby negatively regulates TCR-mediated signaling pathway (PubMed: 18614237). May act at junctions between the membrane and the cytoskeleton.

Research_area:Others

Applications:ELISA

Target_protein:PTPN4

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:1.27ng/L

Detection range:2-600ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Tyrosine-Protein Phosphatase Non-Receptor Type 4

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9WU22

MASS(Da):105,832

GeneID:19258

Synonyms:PTPN 4;PTPN4;Testis-enriched protein tyrosine phosphatase;Tyrosine-protein phosphatase non-receptor type 4

Gene names:PTPN4

Standard solution:640ng/L