Mouse Serum Response Factor, SRF ELISA Kit

SKU: E2466Mo

Size:96 Tests-1 Kit

Background:SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS) (PubMed: 24732378). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration (PubMed: 12732141, PubMed: 19350017, PubMed: 24732378). The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics (PubMed: 24732378). Required for cardiac differentiation and maturation (PubMed: 15169892).

Research_area:Tags & Cell Markers

Applications:ELISA

Target_protein:SRF

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:5.26ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Serum Response Factor

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9JM73

MASS(Da):51,247

GeneID:20807

Synonyms:CCK4;PTK7;Serum response factor;SRF

Gene names:SRF

Standard solution:2400ng/L