Mouse Serine;threonine-protein kinase VRK1,VRK1 ELISA KIT

SKU: E1062Mo

Size:96 Tests-1 Kit

Background:Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity (By similarity). {ECO:0000250, ECO:0000269|PubMed:14645249, ECO:0000269|PubMed:9521809}.

Research_area:

Applications:ELISA

Target_protein:Vrk1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:52.4pg/ml

Detection range:100-6400pg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Serine;threonine-protein kinase VRK1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q80X41

MASS(Da):49741

GeneID:22367

Synonyms:Vrk1

Gene names:Vrk1

Standard solution:12800pg/ml