Mouse Retinoid Acid Receptor Beta, RARB ELISA Kit

SKU: E1547Mo

Size:96 Tests-1 Kit

Background:Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors (By similarity). The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element (By similarity). In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (PubMed:19389355).

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:RARB

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.023ng/ml

Detection range:0.05-10ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Retinoid acid receptor beta

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P22605

MASS(Da):53,331

GeneID:218772

Synonyms:A830025K23;Hap;Nr1b2;Nuclear receptor subfamily 1 group B member 2;RARB;RAR-beta;Retinoic acid receptor beta

Gene names:Rarb

Standard solution:12.8ng/ml