Mouse Receptor Tyrosine-protein Kinase ERBB-3, ERBB3 ELISA Kit

SKU: E2418Mo

Size:96 Tests-1 Kit

Background:Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation.

Research_area:Signal Transduction; Cancer

Applications:ELISA

Target_protein:ERBB3

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.054ng/mL

Detection range:0.1-40ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Receptor tyrosine-protein kinase erbB-3

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q61526

MASS(Da):147,613

GeneID:13867

Synonyms:C76256;Erbb;Erbb-;ERBB3;Erbb-3;Glial growth factor receptor;HER;Her3;Proto-oncogene-like protein c-ErbB-3;Receptor tyrosine-protein kinase erbB-3

Gene names:Erbb3

Standard solution:48ng/mL