Mouse Podocalyxin ELISA Kit PicoKine®

SKU: EK1899

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: Podxl

Specificity: Natural and recombinant mouse Podocalyxin

Background: Podocalyxin-like protein 1 is a protein that in humans is encoded by the PODXL gene. It is mapped to 6 A3.3; 6 12.57 Cm. This gene encodes a member of the CD34 sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Inactivation of the encoding gene in mice leads to anuria, omphalocele and perinatal death. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Immunogen: Expression system for standard: NS0; Immunogen sequence: H22-S404

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Uniprot ID: Q9R0M4

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 27205

Protein Name: Podocalyxin

Gene Full Name: podocalyxin-like

Synonyms: GCTM 2 antigen; Gp200; PC; PCLP; PCLP 1; PCLP1; Podocalyxin; podocalyxin like; Podocalyxin like protein 1; PODXL; RCC marker; Renal Cell Carcinoma marker; TRA 1 81; TRA 1 60; TRA-1-60