Mouse Plasminogen Activator Inhibitor 1, PAI-1 ELISA Kit

SKU: E0088Mo

Size:96 Tests-1 Kit

Background:Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair (By similarity). Involved in cellular and replicative senescence (PubMed:16862142). Plays a role in alveolar type 2 cells senescence in the lung (PubMed:28722352). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:PAI-1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.21ng/ml

Detection range:0.5-100ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:plasminogen activator inhibitor 1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P22777

MASS(Da):45,170

GeneID:18787

Synonyms:Endothelial plasminogen activator inhibitor;PA;PAI;PAI1;PAI-1;Pl;Planh1;Plasminogen activator inhibitor 1;Serpin E1;

Gene names:Serpine1

Standard solution:128ng/ml