Mouse PERQ amino acid-rich with GYF domain-containing protein 2,GIGYF2 ELISA KIT

SKU: E1049Mo

Size:96 Tests-1 Kit

Background:Key component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation (PubMed:26763119). In the 4EHP-GYF2 complex, acts as a factor that bridges EIF4E2 to ZFP36/TTP, linking translation repression with mRNA decay (PubMed:26763119). Also recruits and bridges the association of the 4EHP complex with the decapping effector protein DDX6, which is required for the ZFP36/TTP-mediated down-regulation of AU-rich mRNA (By similarity). May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling, including IGF1 and insulin receptors (PubMed:12771153). {ECO:0000250|UniProtKB:Q6Y7W6, ECO:0000269|PubMed:12771153, ECO:0000269|PubMed:26763119}.

Research_area:

Applications:ELISA

Target_protein:Gigyf2

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.09ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:PERQ amino acid-rich with GYF domain-containing protein 2

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q6Y7W8

MASS(Da):149193

GeneID:227331

Synonyms:Gigyf2 Kiaa0642 Perq2 Tnrc15

Gene names:Gigyf2

Standard solution:24ng/ml