Mouse Low Density Lipoprotein Receptor Related Protein 1,LRP1 ELISA KIT

SKU: E0837Mo

Size:96 Tests-1 Kit

Background:Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development (PubMed:1423604). Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an alpha-2-macroglobulin receptor (By similarity). Acts as TAU/MAPT receptor and controls the endocytosis of TAU/MAPT as well as its subsequent spread (PubMed:32296178). May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission (By similarity). {ECO:0000250|UniProtKB:Q07954, ECO:0000269|PubMed:1423604, ECO:0000269|PubMed:32296178}.; (Microbial infection) Functions as a receptor for Vibrio cholerae cholix toxin and for Pseudomonas aeruginosa exotoxin A. {ECO:0000269|PubMed:1618748, ECO:0000269|PubMed:18276581}.

Research_area:

Applications:ELISA

Target_protein:Lrp1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.28ng/ml

Detection range:0.5-100ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Low Density Lipoprotein Receptor Related Protein 1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q91ZX7

MASS(Da):504742

GeneID:16971

Synonyms:Lrp1 A2mr

Gene names:Lrp1

Standard solution:128ng/ml