Mouse Linker for activation of T cell,LAT ELISA KIT

SKU: E0205Mo

Size:96 Tests-1 Kit

Background:Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules. {ECO:0000269|PubMed:10843385}.

Research_area:

Applications:ELISA

Target_protein:Lat

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.08ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Linker for activation of T cell

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O54957

MASS(Da):26015

GeneID:16797

Synonyms:Lat

Gene names:Lat

Standard solution:24ng/ml