Mouse Leucine-rich PPR Motif-containing Protein, Mitochondrial, LRPPRC ELISA Kit

SKU: E2206Mo

Size:96 Tests-1 Kit

Background:May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters (By similarity). Binds single-stranded DNA.

Research_area:Others

Applications:ELISA

Target_protein:LRPPRC

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:7.17ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Leucine-rich PPR motif-containing protein, mitochondrial

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q6PB66

MASS(Da):156,615

GeneID:72416

Synonyms:130 kDa leucine-rich protein;3110001K13Rik;C76645;Gp130;Leucine-rich PPR motif-containing protein, mitochondrial;Lrp;LRP 130;Lrp130;LRPPRC;Lsfc;mLRP130

Gene names:Lrpprc

Standard solution:3200ng/L