Mouse Inducible T-cell Costimulator, ICOS ELISA Kit

SKU: E2148Mo

Size:96 Tests-1 Kit

Background:Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:ICOS

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.024ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Inducible T-Cell Costimulator

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9WVS0

MASS(Da):22,709

GeneID:54167

Synonyms:Activation-inducible lymphocyte immunomediatory molecule;CCLP;CD antigen CD278;CD28 and CTLA-4-like protein;CD28-related protein 1;CRP-1;ICOS;Inducible T-cell costimulator

Gene names:ICOS

Standard solution:24ng/mL