Mouse Inducible Nitric Oxide Synthase, INOS ELISA Kit

SKU: E0386Mo

Size:96 Tests-1 Kit

Background:Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed: 7503239). In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (PubMed: 16373578). As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (By similarity). Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8 (By similarity).

Research_area:Neuroscience

Applications:ELISA

Target_protein:NOS2

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.16ng/ml

Detection range:0.3-90ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Inducible Nitric Oxide Synthase

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P29477

MASS(Da):130,575

GeneID:18126

Synonyms:Inducible NO Synthase;Inducible NOS;iNOS;MAC-NOS;Macrophage NOS;Nitric oxide Synthase, inducible;NOS 2;NOS type II;NOS2;Peptidyl-cysteine S-nitrosylase NOS2

Gene names:NOS2

Standard solution:96ng/ml