Mouse Gremlin-1, GREM1 ELISA Kit

SKU: E2110Mo

Size:96 Tests-1 Kit

Background:Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop (PubMed: 12808456, PubMed: 15201225). Down-regulates the BMP4 signaling in a dose-dependent manner (PubMed: 15133038). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (By similarity). Acts as inhibitor of monocyte chemotaxis (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:GREM1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:24.34ng/L

Detection range:50-10000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Gremlin-1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O70326

MASS(Da):20,710

GeneID:23892

Synonyms:Cysteine knot superfamily 1, BMP antagonist 1;Down-regulated in Mos-transformed cells protein;GREM 1;GREM1;Gremlin-1

Gene names:GREM1

Standard solution:12800ng/L