Mouse Gamma-Glutamyltranspeptidase 1, GGT1 ELISA Kit

SKU: E2090Mo

Size:96 Tests-1 Kit

Background:Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates and other gamma-glutamyl compounds, such as leukotriene C4 (LTC4). The metabolism of glutathione by GGT1 releases free glutamate and the dipeptide cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Contributes to cysteine homeostasis, glutathione homeostasis and in the conversion of the leukotriene LTC4 to LTD4 (By similarity). Indirectly regulates multiple aspects of skeletal biology (PubMed: 12810527).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:GGT1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.112mU/mL

Detection range:0.2-60mU/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Gamma-Glutamyltranspeptidase 1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q60928

MASS(Da):61,563

GeneID:14598

Synonyms:CD antigen CD224;Gamma-glutamyltransferase 1;Gamma-glutamyltranspeptidase 1;GGT 1;GGT1;Glutathione hydrolase 1 heavy chain;Glutathione hydrolase 1 light chain;Glutathione hydrolase 1 proenzyme;Leukotriene-C4 hydrolase;

Gene names:GGT1

Standard solution:64mU/mL