Mouse Fructose-1,6-bisphosphatase 1,FBP1 ELISA KIT

SKU: E1239Mo

Size:96 Tests-1 Kit

Background:Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain. {ECO:0000269|PubMed:16497803, ECO:0000269|PubMed:18375435, ECO:0000269|PubMed:20719858}.

Research_area:

Applications:ELISA

Target_protein:Fbp1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:54.8pg/ml

Detection range:100-6400pg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Fructose-1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9QXD6

MASS(Da):36912

GeneID:14121

Synonyms:Fbp1 Fbp Fbp3

Gene names:Fbp1

Standard solution:12800pg/ml