Mouse Forkhead box protein O4,FOXO4 ELISA KIT

SKU: E0998Mo

Size:96 Tests-1 Kit

Background:Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity (By similarity). Represses smooth muscle cell differentiation by inhibiting the transcriptional coactivator activity of myocardin. {ECO:0000250|UniProtKB:P98177, ECO:0000269|PubMed:16054032}.

Research_area:

Applications:ELISA

Target_protein:Foxo4

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.1ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Forkhead box protein O4

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9WVH3

MASS(Da):53649

GeneID:54601

Synonyms:Foxo4 Afx Afx1 Fkhr3 Mllt7

Gene names:Foxo4

Standard solution:24ng/ml