Mouse Fibrinogen beta chain,FGB ELISA KIT

SKU: E1041Mo

Size:96 Tests-1 Kit

Background:Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways. {ECO:0000250|UniProtKB:E9PV24}.

Research_area:

Applications:ELISA

Target_protein:Fgb

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:9.19ng/ml

Detection range:18.75-1200ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Fibrinogen beta chain

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8K0E8

MASS(Da):54753

GeneID:110135

Synonyms:Fgb

Gene names:Fgb

Standard solution:2400ng/ml