Mouse E-Cadherin PicoKine® Quick ELISA Kit

SKU: FEK0562

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: CDH1

Specificity: Natural and recombinant mouse E-Cadherin

Background: E-Cadherin, also called Cadherin 1 (CDH1), Uvomorulin or calcium-dependent ashesion protein, epithelial. E-cadherin is a Ca (2+)-dependent epithelial cell-cell adhesion molecule. Downregulation of E-cadherin expression often correlates with strong invasive potential and poor prognosis of human carcinomas. The gene spans a region of approximately 100 kb, and its location on chromosome 16q22.1. It contains 16 exons and a 65-kb-long intron 2. E-cadherin gene mutations may contribute to the development of diffusely growing gastric carcinomas. E-cadherin plays a central part in the process of epithelial morphogenesis and acts as a strong invasion suppressor in experimental tumor cell systems.

Immunogen: Expression system for standard: NS0; Immunogen sequence: D157-V709

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Reference:

Uniprot ID: P09803

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 12550

Protein Name: Cadherin-1

Gene Full Name: cadherin 1

Synonyms: Arc 1; Cadherin 1; CD324; CDH1; CDHE; E cadherin; ECAD; E-cad; E-cadherin; LCAM; UVO; Uvomorulin