GeneBio Systems
Mouse Dickkopf 1,DKK1 ELISA KIT
Mouse Dickkopf 1,DKK1 ELISA KIT
SKU:E0948Mo
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Size:96 Tests-1 Kit
Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed:18524778). Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity (PubMed:26206087). Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning (PubMed:18505822). {ECO:0000269|PubMed:18505822, ECO:0000269|PubMed:18524778, ECO:0000269|PubMed:26206087}.
Research_area:
Applications:ELISA
Target_protein:Dkk1
Reactivity:Mouse
Assay type:Sandwich
Sensitivity:16.15ng/L
Detection range:30-9000ng/L
Sample type:Serum, plasma or other biological fluids
Full product name:Dickkopf 1
Species:Mouse
Storage:2-8ºC
Assay time:1h 30m
UniProt accession:O54908
MASS(Da):29298
GeneID:13380
Synonyms:Dkk1
Gene names:Dkk1
Standard solution:9600ng/L
