Mouse CPE/Carboxypeptidase E ELISA Kit PicoKine®

SKU: EK1888

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: Cpe

Specificity: Natural and recombinant mouse CPE

Background: CPE encodes carboxypeptidase E, a prohormone-processing exopeptidase found in secretory granules of endocrine and neuroendocrine cells. It is mapped to 8 B3.1; 8 32.3 cM. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional enzyme that cleaves the C-terminal basic residues of protein substrates. A missense mutation in this gene is responsible for the obesity phenotype in a mouse model known as the fat mouse. Mice lacking the functional product of this gene exhibit impaired processing of multiple peptide hormones such as proinsulin, prodynorphin, proneurotensin, promelanin-concentrating hormone and pro-opiomelanocortin.

Immunogen: Expression system for standard: NS0; Immunogen sequence: L43-F476

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Reference:

Uniprot ID: Q00493

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 12876

Protein Name: Carboxypeptidase E

Gene Full Name: carboxypeptidase E

Synonyms: Carboxypeptidase E; Carboxypeptidase H; CPE; CPH; Enkephalin convertase