Mouse Collagen alpha-2(IV) chain,COL4A2 ELISA KIT

SKU: E2770Mo

Size:96 Tests-1 Kit

Background:Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.; Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.

Research_area:

Applications:ELISA

Target_protein:COL4A2

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:41.36ng/L

Detection range:75-4800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P08572

MASS(Da):167553

GeneID:1284

Synonyms:COL4A2

Gene names:COL4A2

Standard solution:9600ng/L