Mouse Apoptosis regulator BAX,BAX ELISA KIT

SKU: E1612Mo

Size:96 Tests-1 Kit

Background:Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. BAX deficiency leads to lymphoid hyperplasia and male sterility, because of the cessation of sperm production. {ECO:0000269|PubMed:21060336, ECO:0000269|PubMed:8358790}.

Research_area:

Applications:ELISA

Target_protein:Bax

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.02ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Bcl-2 associated X protein

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q07813

MASS(Da):21395

GeneID:12028

Synonyms:Bax

Gene names:Bax

Standard solution:24ng/ml