Mouse ALCAM/CD166 EZ-Set™ ELISA Kit (DIY Antibody Pairs)

SKU: EZ1184

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: Alcam

Specificity: Natural and recombinant mouse ALCAM

Background: CD166 antigen is a 100-105 kD typeI transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins. In humans it is encoded by the ALCAM gene. The gene was mapped to human chromosome 3q13.1-q13.2 by fluorescence in situ hybridization of cDNA probes to metaphase chromosomes. It is also called CD166 (cluster of differentiation 166), MEMD, SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat. It is expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, neurons, melanoma cells, and also in sweat and sebaceous glands. CD166 protein expression is reported to be upregulated in a cell line deriving from a metastasizing melanoma. CD166 plays an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development. Recently, CD166 has also been used as a potential cancer stem cell marker.

Immunogen: Expression system for standard: NS0; Immunogen sequence: W28-K527

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Reference:

Uniprot ID: Q61490

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 11658

Protein Name: CD166 antigen

Gene Full Name: activated leukocyte cell adhesion molecule

Synonyms: ALCAM; CD166; CD166 antigen; MEMD