MMP8 Antibody - Cat. #: CSB-PA220976

SKU: CSB-PA220976

Size :50ul

Clone Number:

Aliases:CLG 1 antibody; CLG1 antibody; Collagenase 1 antibody; Collagenase 1 neutrophil antibody; HNC antibody; Matrix metallopeptidase 8 (neutrophil collagenase) antibody; Matrix metalloprotease 8 antibody; Matrix metalloproteinase-8 antibody; MMP 8 antibody; MMP-8 antibody; Mmp8 antibody; MMP8_HUMAN antibody; Neutrophil collagenase antibody; PMNL CL antibody; PMNL collagenase antibody; PMNL-CL antibody; PMNLCL antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P22894

Immunogen:Synthetic peptide of Human MMP8

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:1000-1:5000, IHC:1:50-1:200

Background:Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MMP8

Research Areas:Cancer?Cardiovascular?Cell biology;Signal transduction