MICA Polyclonal Antibody

SKU: E-AB-18241

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: MICA

Target Synonym: HLA class I antigen;FLJ36918;FLJ60820;MGC111087;MGC21250;MHC class I chain related gene A protein;MHC class I chain related protein A;MHC class I chain related protein A HLA B HLA C;MHC class I polypeptide related sequence A;MHC class I polypeptide-related sequence A;MHC class I related protein;MIC A;MIC-A;micA;MICA;OTTHUMP00000029088;OTTHUMP00000044528;OTTHUMP00000165170;OTTHUMP00000165172;PERB11.1;Stress inducible class I homolog

Research Areas: Cancer;Immunology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q29983

Accession:

Background: This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.

Concentration: 0.6 mg/mL

Immunogen: Fusion protein of human MICA

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: