MGMT antibody , Cat. # FNab10100

SKU: FNab10100

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Involved in the cellular defense against the biological effects of O6-methylguanine(O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Immunogen:O-6-methylguanine-DNA methyltransferase

Synonyms:MGMT

Observed MW:22 kDa

Uniprot ID:P16455

Reactivity:Human

Tested Application:ELISA, IHC

Recommended dilution:IHC: 1:50 - 1:500

Gene ID:4255

Research Area:Cancer, Immunology, Metabolism