MEK5 antibody , Cat. # FNab05117

SKU: FNab05117

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms(aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

Immunogen:mitogen-activated protein kinase kinase 5

Synonyms:HsT17454, MAP kinase kinase 5, MAP2K5, MAPK/ERK kinase 5, MAPKK 5, MAPKK5, MEK 5, MEK5, MKK5, PRKMK5

Observed MW:50kd

Uniprot ID:Q13163

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IF

Recommended dilution:WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:100

Gene ID:5607

Research Area:Cardiovascular, Metabolism, Signal Transduction