MEK3 Rabbit pAb

SKU: EA345

Size: 100μL

Source:Rabbit

Applications:IHC

Reactivity:Human, Mouse, Rat

Dilution:IHC 1:100-200

Immunogen:Recombinant Protein

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Polyclonal

Isotype:IgG

Concentration:1mg/mL

Observed_band(KD):34,39kDa

Human_gene_id:5606

Human_swiss_prot_no:P46734

Subcellular_location:Cytosol,Nucleus

Other_name:MAP2K3; MKK3; PRKMK3; Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPKK3; MAPK/ERK kinase 3

Background:Three alternatively spliced transcript variants of MEK3 encoding distinct isoforms have been reported. Isoform B utilizes a different start codon compared to isoform C resulting in the production of a N-terminal segment of isoform B which is shorter and distinct from isoform C . MEK3b is the predominant form of MEK3 and strongly activates p38 MAP kinase .