MCM3 Polyclonal Antibody

SKU: E-AB-10453

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:MCM3

Target Synonym:Cervical cancer proto oncogene 5;DNA polymerase alpha holoenzyme associated P1;DNA polymerase alpha holoenzyme associated protein P1;DNA polymerase alpha holoenzyme-associated protein P1;DNA replication factor MCM3;DNA replication licensing factor mcm3;HCC 5;HCC5;hRlf beta subunit;Human cervical cancer proto oncogene 5;MCM 3;mcm3;MCM3 minichromosome maintenance deficient 3;MCM3;MGC1157;Minichromosome maintenance complex component 3;Minichromosome maintenance deficient 3;Minichromosome maintenance protein 3;P1 h;P1 MCM3;P1 Protein;P1-MCM3;P1.h;p102;P102 protein;Replication licensing factor beta subunit;RLF beta subunit;RLF subunit beta;RLFB

Research Areas:Cancer;Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P25205

Accession:

Background:The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly witHuman, MouseCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.

Concentration:0.3 mg/mL

Immunogen:Recombinant protein of human MCM3

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000

Calculated MW:91kDa

ObservedMW: